Crystal structure of the kinase domain of type I activin receptor (ACVR1) in complex with FKBP12 and dorsomorphin
The structure was published by Chaikuad, A., Alfano, I., Kerr, G., et al., Knapp, S., Knaus, P., and Bullock, A.N., in 2012 in a paper entitled "Structure of the Bone Morphogenetic Protein Receptor ALK2 and Implications for Fibrodysplasia Ossificans Progressiva." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.35 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Activin receptor type-1 and Peptidyl-prolyl cis-trans isomerase FKBP1A.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: