3h73 Summary


Crystal structure of Streptococcus pneumoniae D39 neuraminidase A precursor (NanA) in complex with DANA

The structure was published by Hsiao, Y.-S., Parker, D., Ratner, A.J., Prince, A., and Tong, L., in 2009 in a paper entitled "Crystal structures of respiratory pathogen neuraminidases" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.7 Å and deposited in 2009.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Sialidase A.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Sialidase A P62576 (317-793) (NANA_STRR6)search Streptococcus pneumoniae R6search < 90% 477 100%
B Sialidase A P62576 (317-793) (NANA_STRR6)search Streptococcus pneumoniae R6search < 90% 477 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P62576 (317 - 793) Sialidase A Streptococcus pneumoniae R6

Chain Structural classification (CATH) Sequence family (Pfam)
A, B Neuraminidasesearch BNR/Asp-box repeatsearch

Chain ID Molecular function (GO)
A, B (P62576) exo-alpha-sialidase activitysearch

Chain InterPro annotation
A, B Sialidasessearch Sialidase familysearch