Aurora A inhibitor complex
The structure was published by Aliagas-Martin, I., Burdick, D., Corson, L., et al., Zhang, B., Zhu, B.Y., and Cochran, A.G., in 2009 in a paper entitled "A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Serine/threonine-protein kinase 6.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: