3h0f Summary


Crystal structure of the human Fyn SH3 R96W mutant

A publication describing this structure is not available. The depositing authors are Ponchon, L.search; Hoh, F.search; Labesse, G.search; Dumas, C.search; Arold, S.T.search

This crystal structure was determined using X-ray diffraction at a resolution of 2.61 Å and deposited in 2009.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Proto-oncogene tyrosine-protein kinase Fyn. This molecule has the UniProt identifier P06241 (FYN_HUMAN)search. The sample contained 73 residues which is < 90% of the natural sequence. Out of 73 residues 59 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Proto-oncogene tyrosine-protein kinase Fyn P06241 (73-142) (FYN_HUMAN)search Homo sapienssearch < 90% 73 80%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P06241 (73 - 142) Proto-oncogene tyrosine-protein kinase Fyn Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A SH3 Domainssearch SH3 domainsearch
Chain InterPro annotation
A SH3 domainsearch