3gvl Summary


Crystal Structure of endo-neuraminidaseNF

The structure was published by Schulz, E.C., Schwarzer, D., Frank, M., et al., Dickmanns, A., Gerardy-Schahn, R., and Ficner, R., in 2010 in a paper entitled "Structural basis for the recognition and cleavage of polysialic acid by the bacteriophage K1F tailspike protein EndoNF." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.41 Å and deposited in 2009.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Endo-N-acetylneuraminidase. This molecule has the UniProt identifier Q04830 (ENAN_BPK1F)search. The sample contained 670 residues which is < 90% of the natural sequence. Out of 670 residues 670 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Endo-N-acetylneuraminidase Q04830 (246-910) (ENAN_BPK1F)search Enterobacteria phage K1Fsearch < 90% 670 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q04830 (246 - 910) Endo-N-acetylneuraminidase Enterobacteria phage K1F

Chain Structural classification (CATH) Sequence family (Pfam)
A Endo-alpha-sialidase; domain 1search, Neuraminidasesearch, Elongation Factor Tu (Ef-tu); domain 3search Beta barrel domain of bacteriophage endosialidasesearch, Catalytic beta propeller domain of bacteriophage endosialidasesearch, N terminal extension of bacteriophage endosialidasesearch, Catalytic domain of bacteriophage endosialidasesearch
Chain InterPro annotation
A Glycosyl hydrolase 58search Sialidasessearch ATP synthase subunit alpha-like domainsearch Endosialidase, beta barrel domainsearch Endosialidase, beta propeller domainsearch Endosialidase, N-terminal extension domainsearch Endosialidase, C-terminal domainsearch