Crystal structure of the inactive EGFR kinase domain in complex with AMP-PNP
The structure was published by Jura, N., Endres, N.F., Engel, K., et al., Wemmer, D.E., Zhang, X., and Kuriyan, J., in 2009 in a paper entitled "Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.955 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Epidermal growth factor receptor and Unknown peptide.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: