3gt7

X-ray diffraction
2.3Å resolution

CRYSTAL STRUCTURE OF SIGNAL RECEIVER DOMAIN OF SIGNAL TRANSDUCTION HISTIDINE KINASE FROM Syntrophus aciditrophicus

Released:
Source organism: Syntrophus aciditrophicus SB
Entry authors: Patskovsky Y, Toro R, Morano C, Freeman J, Hu S, Sauder JM, Burley SK, Almo SC, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed:
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173709 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
histidine kinase Chain: A
Molecule details ›
Chain: A
Length: 154 amino acids
Theoretical weight: 17.53 KDa
Source organism: Syntrophus aciditrophicus SB
Expression system: Escherichia coli
UniProt:
  • Canonical: Q2LQE8 (Residues: 8-150; Coverage: 20%)
Gene name: SYN_02576
Sequence domains: Response regulator receiver domain
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P6522
Unit cell:
a: 82.434Å b: 82.434Å c: 76.445Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.222 0.221 0.238
Expression system: Escherichia coli