Crystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 beta) in complex with Nilotinib
A publication describing this structure is not available. The depositing authors are Filippakopoulos, P.; Barr, A.; Fedorov, O.; Keates, T.; Soundararajan, M.; Elkins, J.; Salah, E.; Burgess-Brown, N.; Ugochukwu, E.; Pike, A.C.W.; Muniz, J.; Roos, A.; Chaikuad, A.; von Delft, F.; Arrowsmith, C.H.; Edwards, A.M.; Weigelt, J.; Bountra, C.; Knapp, S.; Structural Genomics Consortium (SGC)
This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Mitogen-activated protein kinase 11. This molecule has the UniProt identifier Q15759 (MK11_HUMAN). The sample contained 348 residues which is 95% of the natural sequence. Out of 348 residues 328 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: