3gf1 Summary

pdbe.org/3gf1
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SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY

The structure was published by Cooke, R.M., Harvey, T.S., and Campbell, I.D., in 1991 in a paper entitled "Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1991.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of INSULIN-LIKE GROWTH FACTOR I. This molecule has the UniProt identifier P05019 (IGF1_HUMAN)search. The sample contained 70 residues which is < 90% of the natural sequence. Out of 70 residues 70 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A INSULIN-LIKE GROWTH FACTOR I P05019 (49-118) (IGF1_HUMAN)search Homo sapienssearch < 90% 70 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P05019 (49 - 118) INSULIN-LIKE GROWTH FACTOR I Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Insulin-likesearch Insulin-like, subunit Esearch Insulin/IGF/Relaxin familysearch

Chain ID Molecular function (GO) Cellular component (GO)
A (P05019) growth factor activitysearch hormone activitysearch extracellular spacesearch extracellular regionsearch

Chain InterPro annotation
A Insulin-likesearch Insulin-like growth factor Isearch Insulin-like growth factorsearch Insulin familysearch Insulin, conserved sitesearch