Src Thr338Ile inhibited in the DFG-Asp-Out conformation
The structure was published by Seeliger, M.A., Ranjitkar, P., Kasap, C., et al., Shah, N.P., Kuriyan, J., and Maly, D.J., in 2009 in a paper entitled "Equally potent inhibition of c-Src and Abl by compounds that recognize inactive kinase conformations" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.35 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Proto-oncogene tyrosine-protein kinase Src.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: