3fz8 Summary

pdbe.org/3fz8
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Crystal structure of glutamate decarboxylase beta from Escherichia coli: reduced Schiff base with PLP

The structure was published by Malashkevich, V.N., De Biase, D., and Bossa, F., in in a paper entitled "Crystal structure of glutamate decarboxylase beta from Escherichia coli: reduced Schiff base with PLP" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.0 Å and deposited in 2009.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Glutamate decarboxylase beta.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homohexamers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Glutamate decarboxylase beta P69910 (1-466) (DCEB_ECOLI)search Escherichia coli K-12search 97% 466 99%
B Glutamate decarboxylase beta P69910 (1-466) (DCEB_ECOLI)search Escherichia coli K-12search 97% 466 99%
C Glutamate decarboxylase beta P69910 (1-466) (DCEB_ECOLI)search Escherichia coli K-12search 97% 466 99%
D Glutamate decarboxylase beta P69910 (1-466) (DCEB_ECOLI)search Escherichia coli K-12search 97% 466 99%
E Glutamate decarboxylase beta P69910 (1-466) (DCEB_ECOLI)search Escherichia coli K-12search 97% 466 99%
F Glutamate decarboxylase beta P69910 (1-466) (DCEB_ECOLI)search Escherichia coli K-12search 97% 466 99%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P69910 (1 - 466) Glutamate decarboxylase beta Escherichia coli K-12

Chain Sequence family (Pfam)
A, B, C, D, E, F (P69910) PF00282: Pyridoxal-dependent decarboxylase conserved domainsearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A, B, C, D, E, F (P69910) carboxylic acid metabolic processsearch glutamate metabolic processsearch intracellular pH elevationsearch pyridoxal phosphate bindingsearch catalytic activitysearch carboxy-lyase activitysearch glutamate decarboxylase activitysearch lyase activitysearch cytoplasmsearch membranesearch cytosolsearch

Chain InterPro annotation
A, B, C, D, E, F Pyridoxal phosphate-dependent decarboxylasesearch Glutamate decarboxylasesearch Pyridoxal phosphate-dependent transferase, major region, subdomain 1search Pyridoxal phosphate-dependent transferasesearch Pyridoxal-phosphate binding sitesearch