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Crystal structure of glutamate decarboxylase beta from Escherichia coli: reduced Schiff base with PLP

X-ray diffraction
3Å resolution
PDB entry 3fz8 coloured by chain, front view.
PDB entry 3fz8 coloured by chain, side view.
PDB entry 3fz8 coloured by chain, top view.
Source organism: Escherichia coli K-12
Assembly composition:
homo hexamer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Glutamate decarboxylase beta
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Multimeric state: homo hexamer
Accessible surface area: 86425.99 Å2
Buried surface area: 50771.15 Å2
Dissociation area: 7,310.32 Å2
Dissociation energy (ΔGdiss): 71.62 kcal/mol
Dissociation entropy (TΔSdiss): 33 kcal/mol
Symmetry number: 6
PDBe Complex ID: PDB-CPX-159688

Macromolecules

Glutamate decarboxylase beta
Chains: A, B, C, D, E, F
Length: 466 amino acids
Theoretical weight: 52.73 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
  • Canonical: P69910 (Residues: 1-466; Coverage: 100%)
Gene names: JW1488, b1493, gadB
Pfam: Pyridoxal-dependent decarboxylase conserved domain
InterPro:
CATH:
Glutamate decarboxylase beta in PDB entry 3fz8, assembly 1, front view.
Glutamate decarboxylase beta in PDB entry 3fz8, assembly 1, side view.
Glutamate decarboxylase beta in PDB entry 3fz8, assembly 1, top view.
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