Crystal structure of HNF4a LBD in complex with the ligand and the coactivator PGC-1a fragment
The structure was published by Rha, G.B., Wu, G., Shoelson, S.E., and Chi, Y.I., in 2009 in a paper entitled "Multiple binding modes between HNF4alpha and the LXXLL motifs of PGC-1alpha lead to full activation" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Hepatocyte nuclear factor 4-alpha and PPARgamma Coactivator-1a (PGC-1a).
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: