› 3fd4

X-ray diffraction
2.4Å resolution

Crystal Structure of Epstein-Barr virus gp42 protein

Released:
DOI: 10.2210/pdb3fd4/pdb
PDB entry 3fd4 coloured by chain, front view.
PDB entry 3fd4 coloured by chain, side view.
PDB entry 3fd4 coloured by chain, top view.
Source organism: Human herpesvirus 4 strain B95-8
Primary publication:
Structure of Epstein-Barr virus glycoprotein 42 suggests a mechanism for triggering receptor-activated virus entry.
Kirschner AN, Sorem J, Longnecker R, Jardetzky TS
Structure 17 223-33 (2009)
PMID: 19217393

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136647 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Soluble gp42 Chains: A, B
Molecule details ›
Chains: A, B
Length: 191 amino acids
Theoretical weight: 21.63 KDa
Source organism: Human herpesvirus 4 strain B95-8
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P03205 (Residues: 33-223; Coverage: 86%)
Gene name: BZLF2
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 64.792Å b: 67.469Å c: 79.463Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.217 0.215 0.242
Expression system: Spodoptera frugiperda

Quick links

Citations

11 review citations

Viral membrane fusion.
Harrison SC. (2015)
10 more

10 mentions without citation

Fusing structure and function: a structural view of the herpesvirus entry machinery.
Connolly et al. (2011)
9 more