Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor
The structure was published by Bonafoux, D., Chuaqui, C., Boriack-Sjodin, P.A., et al., Hetu, G., Ling, L., and Lee, W.C., in 2009 in a paper entitled "2-Aminoimidazoles inhibitors of TGF-beta receptor 1." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.35 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of TGF-beta receptor type-1.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: