Crystal structure of thymidine kinase from Herpes simplex virus type 1 in complex with N-methyl-DHBT
The structure was published by Martic, M., Pernot, L., Westermaier, Y., et al., Raic-Malic, S., Scapozza, L., and Ametamey, S., in 2011 in a paper entitled "Synthesis, crystal structure, and in vitro biological evaluation of C-6 pyrimidine derivatives: new lead structures for monitoring gene expression in vivo." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Thymidine kinase.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: