› 3eyx

X-ray diffraction
2.04Å resolution

Crystal structure of Carbonic Anhydrase Nce103 from Saccharomyces cerevisiae

Released:
DOI: 10.2210/pdb3eyx/pdb
PDB entry 3eyx coloured by chain, front view.
PDB entry 3eyx coloured by chain, side view.
PDB entry 3eyx coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structural insights into the substrate tunnel of Saccharomyces cerevisiae carbonic anhydrase Nce103.
Teng YB, Jiang YL, He YX, He WW, Lian FM, Chen Y, Zhou CZ
BMC Struct Biol 9 67 (2009)
PMID: 19852838

Function and Biology Details

Reaction catalysed: 
H(2)CO(3) = CO(2) + H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156830 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase Chains: A, B
Molecule details ›
Chains: A, B
Length: 216 amino acids
Theoretical weight: 24.56 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P53615 (Residues: 14-221; Coverage: 94%)
Gene names: N2695, NCE103, NCE3, YNL036W
Sequence domains: Carbonic anhydrase
Structure domains: Carbonic anhydrase

Ligands and Environments

3 bound ligands:
Ligand ZN 2 x ZN
Ligand ACT 2 x ACT
Ligand EDO 4 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2221
Unit cell:
a: 60.57Å b: 155.73Å c: 89.69Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.197 0.241
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Gates of enzymes.
Gora et al. (2013)
2 more

6 mentions without citation

Phenols and Polyphenols as Carbonic Anhydrase Inhibitors.
Karioti et al. (2016)
5 more