› 3etw

X-ray diffraction
2Å resolution

Crystal Structure of bacterial adhesin FadA

Released:
DOI: 10.2210/pdb3etw/pdb
PDB entry 3etw coloured by chain, front view.
PDB entry 3etw coloured by chain, side view.
PDB entry 3etw coloured by chain, top view.
Source organism: Fusobacterium nucleatum
Primary publication:
Crystal structure of FadA adhesin from Fusobacterium nucleatum reveals a novel oligomerization motif, the leucine chain.
Nithianantham S, Xu M, Yamada M, Ikegami A, Shoham M, Han YW
J Biol Chem 284 3865-72 (2009)
PMID: 18996848

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177247 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adhesion protein FadA Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.67 KDa
Source organism: Fusobacterium nucleatum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5I6B0 (Residues: 19-129; Coverage: 100%)
Gene names: DNF10_04660, fadA
Sequence domains: Adhesion protein FadA
Structure domains: Helix Hairpins

Ligands and Environments

1 bound ligand:
Ligand SCN 1 x SCN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM, ALS BEAMLINE 4.2.2
Spacegroup: P61
Unit cell:
a: 59.34Å b: 59.34Å c: 126.374Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.251 0.225 0.254
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Mobile microbiome: oral bacteria in extra-oral infections and inflammation.
Han et al. (2013)
10 more

6 mentions without citation

Crystal structure of FadA adhesin from Fusobacterium nucleatum reveals a novel oligomerization motif, the leucine chain.
Nithianantham et al. (2009)
5 more