› 3enj

X-ray diffraction
1.78Å resolution

Structure of Pig Heart Citrate Synthase at 1.78 A resolution

Released:
DOI: 10.2210/pdb3enj/pdb
PDB entry 3enj coloured by chain, front view.
PDB entry 3enj coloured by chain, side view.
PDB entry 3enj coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Structure of pig heart citrate synthase at 1.78 A resolution.
Larson SB, Day JS, Nguyen C, Cudney R, McPherson A
Acta Crystallogr Sect F Struct Biol Cryst Commun 65 430-4 (2009)
PMID: 19407370

Function and Biology Details

Reaction catalysed: 
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133671 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Citrate synthase, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 437 amino acids
Theoretical weight: 48.98 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P00889 (Residues: 28-464; Coverage: 94%)
Gene name: CS
Sequence domains: Citrate synthase, C-terminal domain
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand CYS 1 x CYS
Ligand CL 1 x CL
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P41212
Unit cell:
a: 76.34Å b: 76.34Å c: 198.15Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.179 0.222

Quick links

Citations

4 citation in other articles

Oligomeric assembly is required for chaperone activity of the filamentous γ-prefoldin.
Glover et al. (2015)
3 more

8 mentions without citation

Widespread and enzyme-independent Nε-acetylation and Nε-succinylation of proteins in the chemical conditions of the mitochondrial matrix.
Wagner et al. (2013)
7 more