spacer Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with PP494, a multitargeted kinase inhibitor
Experimental details
Structure factors Download
Spacegroup P 1
Parameters
a:42.296Å b:62.985Å c:74.144Å
α:101.14° β:92.15° γ:90.12°
Refinement
Highest Resolution 2.66 Å
Lowest Resolution 43.15 Å
Number of reflections Observed:20103 (97.85% complete) R-free:1080 (5.1%)
R-values R = 0.21 Rwork = 0.2 Rfree = 0.25
Diffraction
Dataset 1
Temperature (K) Source Source type Wavelength (Å)
100.0 Synchrotron ALS BEAMLINE 8.2.1 1.000

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