spacer Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with PP494, a multitargeted kinase inhibitor
EDS summary (view at EDS site)
Original refinement program REFMAC 5.5.0044
Resolution from map calculation 2.66 - 43.15 Å
R value for map 0.209
Completeness of data 97.8 %
Number of reflections 21183 (21649 in original CIF file)
Yeates <|L|> 0.498
Yeates <L^2> 0.329
Wilson plot B-factor 43.1 Å2
Bulk-solvent scale factor (k) 0.333 e/Å3
Bulk-solvent B-factor 9.6 Å2
Mean (st. dev.) values for non-water residues:
Real-space R-value 0.153 (0.045)
Real-space correlation coefficient 0.957 (0.028)
Occupancy-weighted average temperature factor 14.2 (4.4) Å2

View more detailed information at EDS.