3ehq Summary


Crystal Structure of Human Osteoclast Stimulating Factor

The structure was published by Tong, S., Zhou, H., Gao, Y., et al., Zhang, X., Teng, M., and Niu, L., in 2009 in a paper entitled "Crystal structure of human osteoclast stimulating factor" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.57 Å and deposited in 2008.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Osteoclast-stimulating factor 1.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Osteoclast-stimulating factor 1 Q92882 (1-214) (OSTF1_HUMAN)search Homo sapienssearch 100% 222 81%
B Osteoclast-stimulating factor 1 Q92882 (1-214) (OSTF1_HUMAN)search Homo sapienssearch 100% 222 81%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q92882 (1 - 214) Osteoclast-stimulating factor 1 Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A, B (Q92882) SH3 Domainssearch, Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeatsearch PF00018: SH3 domainsearch, PF12796: Ankyrin repeats (3 copies)search, PF13857: Ankyrin repeats (many copies)search

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A, B (Q92882) SH3 domain bindingsearch protein bindingsearch intracellularsearch extracellular vesicular exosomesearch cytoplasmsearch ossificationsearch signal transductionsearch

Chain InterPro annotation
A, B SH3 domainsearch Ankyrin repeatsearch Ankyrin repeat-containing domainsearch