3eg1 Summary details

pdbe.org/3eg1/summary_details
spacer Crystal structure of the N114Q mutant of ABL-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions
Summary
Header Transferase/Signaling proteinsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.85 Å, R-factor: 19.2%, Free R-factor: 24.8%, Spacegroup: P 21 21 21
Released 15/09/2009, deposition: 10/09/2008, last revision: 13/07/2011
Authors Camara-Artigas, A.search
Primary citation Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.
J.BIOL.CHEM.search vol:285, pag:2823-2833 (2010) [PubMed 19906645 ]search
Keywords betasearch, SH3 domainsearch, ATP-bindingsearch, Cell adhesionsearch, Cytoskeletonsearch, Kinasesearch, Lipoproteinsearch, Magnesiumsearch, Manganesesearch, Metal-bindingsearch, Myristatesearch, Nucleotide-bindingsearch, Nucleussearch, Phosphoproteinsearch, Proto-oncogenesearch, SH2 domainsearch, Transferasesearch, Tyrosine-protein kinasesearch, SIGNALING PROTEINsearch, Transferase-Signaling protein COMPLEXsearch
EC 2.7.10.2 ExPASy BRENDA search (A B)
Organism Homo sapiens(human) 9606search(A B)
UniProt P00519search (A B)
Solvent A, B, C, D
Related entries 2o88, 1bbz, 3eg0, 3eg2, 3eg3
Polymers
Chain Id Name Type UniProt Residues in sample sequence % of sample sequence observed
A, B Proto-oncogene tyrosine-protein kinase ABL1 Protein P00519 (ABL1_HUMAN)search
63 92%
C, D p41 peptide Protein
11 100%
Heterogens
Chain Id Name Ligands
A, B SULFATE ION SO4 search
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