Crystal structure of the N114Q mutant of ABL-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions
The structure was published by Palencia, A., Camara-Artigas, A., Pisabarro, M.T., Martinez, J.C., and Luque, I., in 2010 in a paper entitled "Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.85 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Proto-oncogene tyrosine-protein kinase ABL1 and p41 peptide.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: