Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors
The structure was published by Rouse, M.B., Seefeld, M.A., Leber, J.D., et al., Choudhry, A.E., Schaber, M.D., and Heerding, D.A., in 2009 in a paper entitled "Aminofurazans as potent inhibitors of AKT kinase" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.7 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely RAC-beta serine/threonine-protein kinase and Glycogen synthase kinase-3 beta peptide.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: