Crystal structure of catalytic subunit of human protein kinase CK2alpha prime with a potent indazole-derivative inhibitor
The structure was published by Nakaniwa, T., Kinoshita, T., Sekiguchi, Y., et al., Ohno, H., Hirasawa, A., and Tsujimoto, G., in 2009 in a paper entitled "Structure of human protein kinase CK2alpha2 with a potent indazole-derivative inhibitor" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.2 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Casein kinase II subunit alpha'. This molecule has the UniProt identifier P19784 (CSK22_HUMAN). The sample contained 339 residues which is 95% of the natural sequence. Out of 339 residues 333 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: