› › Structure analysis

Crystal structure of human fumarate hydratase

X-ray diffraction
1.95Å resolution
PDB entry 3e04 coloured by chain, front view.
PDB entry 3e04 coloured by chain, side view.
PDB entry 3e04 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Fumarate hydratase, mitochondrial
hide full assembly name
Multimeric state: homo tetramer
Accessible surface area: 51686.21 Å2
Buried surface area: 28709.53 Å2
Dissociation area: 8,093.42 Å2
Dissociation energy (ΔGdiss): 131.25 kcal/mol
Dissociation entropy (TΔSdiss): 17.39 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-139860

Macromolecules

Fumarate hydratase, mitochondrial
Chains: A, B, C, D
Length: 490 amino acids
Theoretical weight: 52.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07954 (Residues: 44-510; Coverage: 92%)
Gene name: FH
Pfam:
InterPro:
CATH:
Fumarate hydratase, mitochondrial in PDB entry 3e04, assembly 1, front view.
Fumarate hydratase, mitochondrial in PDB entry 3e04, assembly 1, side view.
Fumarate hydratase, mitochondrial in PDB entry 3e04, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links