› 3dzb

X-ray diffraction
2.46Å resolution

Crystal structure of Prephenate dehydrogenase from Streptococcus thermophilus

Released:
DOI: 10.2210/pdb3dzb/pdb
PDB entry 3dzb coloured by chain, front view.
PDB entry 3dzb coloured by chain, side view.
PDB entry 3dzb coloured by chain, top view.
Source organism: Streptococcus thermophilus LMG 18311
Entry authors: Zhang Z, Eswaramoorthy S, Burley SK, Swaminathan S, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Reaction catalysed: 
Prephenate + NAD(+) = 4-hydroxyphenylpyruvate + CO(2) + NADH
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177600 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Prephenate/arogenate dehydrogenase domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 317 amino acids
Theoretical weight: 35.78 KDa
Source organism: Streptococcus thermophilus LMG 18311
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5M554 (Residues: 2-308; Coverage: 83%)
Gene names: stu0642, tyrA
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 18 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P21212
Unit cell:
a: 83.906Å b: 145.005Å c: 56.227Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.271 0.234 0.278
Expression system: Escherichia coli

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