Crystal structure of the VEGFR2 kinase domain in complex with a benzisoxazole inhibitor
The structure was published by Kunz, R.K., Rumfelt, S., Chen, N., et al., Xu, Y., Ng, G.Y., and Hu, E., in 2008 in a paper entitled "Discovery of amido-benzisoxazoles as potent c-Kit inhibitors." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.9 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Vascular endothelial growth factor receptor 2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: