P38 complex with a phthalazine inhibitor
The structure was published by Herberich, B., Cao, G.Q., Chakrabarti, P.P., et al., Middleton, S., Wong, L.M., and Tasker, A.S., in 2008 in a paper entitled "Discovery of highly selective and potent p38 inhibitors based on a phthalazine scaffold." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.9 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Mitogen-activated protein kinase 14.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: