spacer Crystal structure of mutant ABL kinase domain in complex with small molecule fragment
Accession P00520search
Keywords DNA damage, Magnesium, Kinase, Manganese, Complete proteome, Chromosomal rearrangement, Transferase, Proto-oncogene, Tyrosine-protein kinase, Lipoprotein, Cell adhesion, DNA-binding, Ubl conjugation, Reference proteome, Metal-binding, SH3 domain, Acetylation, Endocytosis, Myristate, Apoptosis, Autophagy, DNA repair, Nucleotide-binding, Mitochondrion, Alternative splicing, Cytoplasm, 3D-structure, ATP-binding, Phosphoprotein, SH2 domain, Cytoskeleton, Nucleus
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Polymers A B
Enzyme nomenclature
EC number ExPASy BRENDA search
Polymers B, A
Name non-specific protein-tyrosine kinase
Comment Unlike EC, receptor protein-tyrosine kinase, this protein-tyrosine kinase does not have a transmembrane domain. In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into ten families.