3da2 Summary

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X-ray structure of human carbonic anhydrase 13 in complex with inhibitor

A publication describing this structure is not available. The depositing authors are Pilka, E.S.search; Picaud, S.S.search; Yue, W.W.search; King, O.N.F.search; Bray, J.E.search; Filippakopoulos, P.search; Roos, A.K.search; Pike, A.C.W.search; von Delft, F.search; Arrowsmith, C.H.search; Wikstrom, M.search; Edwards, A.M.search; Bountra, C.search; Oppermann, U.search; Structural Genomics Consortium (SGC)search

This crystal structure was determined using X-ray diffraction at a resolution of 2.05 Å and deposited in 2008.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Carbonic anhydrase 13.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Carbonic anhydrase 13 Q8N1Q1 (1-261) (CAH13_HUMAN)search Homo sapienssearch 100% 262 100%
B Carbonic anhydrase 13 Q8N1Q1 (1-261) (CAH13_HUMAN)search Homo sapienssearch 100% 262 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q8N1Q1 (1 - 261) Carbonic anhydrase 13 Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A, B (Q8N1Q1) Carbonic Anhydrase IIsearch PF00194: Eukaryotic-type carbonic anhydrasesearch

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A, B (Q8N1Q1) cytosolsearch myelin sheathsearch zinc ion bindingsearch carbonate dehydratase activitysearch metal ion bindingsearch lyase activitysearch one-carbon metabolic processsearch small molecule metabolic processsearch bicarbonate transportsearch

Chain InterPro annotation
A, B Alpha carbonic anhydrasesearch Carbonic anhydrase, alpha-class, conserved sitesearch Carbonic anhydrase, alpha-classsearch