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TR Variant D355R

X-ray diffraction
2.2Å resolution
PDB entry 3d57 coloured by chain, front view.
PDB entry 3d57 coloured by chain, side view.
PDB entry 3d57 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Thyroid hormone receptor beta
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Multimeric state: homo dimer
Accessible surface area: 22653.67 Å2
Buried surface area: 3223.55 Å2
Dissociation area: 741.97 Å2
Dissociation energy (ΔGdiss): 1.21 kcal/mol
Dissociation entropy (TΔSdiss): 13.03 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-145484

Macromolecules

Thyroid hormone receptor beta
Chains: A, B
Length: 266 amino acids
Theoretical weight: 30.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10828 (Residues: 209-460; Coverage: 55%)
Gene names: ERBA2, NR1A2, THR1, THRB
Pfam: Ligand-binding domain of nuclear hormone receptor
InterPro:
CATH: Retinoid X Receptor
Thyroid hormone receptor beta in PDB entry 3d57, assembly 1, front view.
Thyroid hormone receptor beta in PDB entry 3d57, assembly 1, side view.
Thyroid hormone receptor beta in PDB entry 3d57, assembly 1, top view.
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