› › Structure analysis

Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with [7-(2-{2-[3-(3-chloro-phenyl)-ureido]-thiazol-5-yl}-ethylamino)-pyrazolo[4,3-d]pyrimidin-1-yl]-acetic acid

X-ray diffraction
2.5Å resolution
PDB entry 3d2k coloured by chain, front view.
PDB entry 3d2k coloured by chain, side view.
PDB entry 3d2k coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Aurora kinase A
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 12395.53 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-161308

Macromolecules

Aurora kinase A
Chain: A
Length: 272 amino acids
Theoretical weight: 31.55 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P97477 (Residues: 116-381; Coverage: 67%)
Gene names: Aik, Airk1, Ark1, Aura, Aurka, Ayk1, Btak, Iak1, Stk15, Stk6
Pfam: Protein kinase domain
InterPro:
CATH:
Aurora kinase A in PDB entry 3d2k, assembly 1, front view.
Aurora kinase A in PDB entry 3d2k, assembly 1, side view.
Aurora kinase A in PDB entry 3d2k, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links