3d0n Summary


Crystal structure of human carbonic anhydrase XIII

The structure was published by Di Fiore, A., Monti, S.M., Hilvo, M., et al., Scozzafava, A., Supuran, C.T., and De Simone, G., in 2008 in a paper entitled "Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.55 Å and deposited in 2008.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Carbonic anhydrase 13.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Carbonic anhydrase 13 Q8N1Q1 (1-262) (CAH13_HUMAN)search Homo sapienssearch 100% 264 99%
B Carbonic anhydrase 13 Q8N1Q1 (1-262) (CAH13_HUMAN)search Homo sapienssearch 100% 264 99%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q8N1Q1 (1 - 262) Carbonic anhydrase 13 Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A, B (Q8N1Q1) Carbonic Anhydrase IIsearch PF00194: Eukaryotic-type carbonic anhydrasesearch

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A, B (Q8N1Q1) cytosolsearch myelin sheathsearch lyase activitysearch metal ion bindingsearch carbonate dehydratase activitysearch zinc ion bindingsearch small molecule metabolic processsearch one-carbon metabolic processsearch bicarbonate transportsearch

Chain InterPro annotation
A, B Alpha carbonic anhydrasesearch Carbonic anhydrase, alpha-class, conserved sitesearch Carbonic anhydrase, alpha-classsearch