 |
PDBe Entry: 3czs 
Golgi alpha-mannosidase II (D204A nucleophile mutant)
 |
HYDROLASE
|
|
X-RAY DIFFRACTION
|
|
Resolution: 1.3 Å, R-factor: 19.3%, Free R-factor: 21.5%, Spacegroup: P 21 21 21
|
|
24/06/2008, deposition: 29/04/2008, last revision: 24/02/2009
|
|
Shah, N.; Rose, D.R.
|
Golgi alpha-mannosidase II cleaves two sugars sequentially in the same catalytic site.
PROC.NATL.ACAD.SCI.USA vol:105, pag:9570-9575 (2008) [PubMed ID 18599462 ]
|
|
hydrolase, glycosyl hydrolase, mannosidase, N-terminal alpha-beta domain, three helix bundle, 2 C-terminal beta barrels
|
|
3.2.1.114 ExPASy BRENDA (A)
|
|
Drosophila melanogaster(fruit fly) 7227(A)
|
|
Alpha-mannosidase 2 (EC 3.2.1.114) (Alpha-mannosidase II) (AMAN II) (MAN II) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) (Golgi alpha-mannosidase II) Q24451 (A)
|
|
A
|
|
1hty, 1hww, 1hxk, 1ps2, 1qwn, 1qwu, 1qx1, 1r33, 1r34, 2alw, 2f7o, 2f7p, 2f7q, 2f7r, 3bub, 3bud, 3bui, 3bup, 3buq, 3bvt, 3bvu, 3bvv, 3bvw, 3bvx, 3cv5, 3czn, 3d4y, 3d4z, 3d50, 3d51, 3d52
|
| A |
Alpha-mannosidase 2 |
Protein |
Q24451 (MAN2_DROME)
|
1045 |
97% |
|
| A |
SUGAR (N-ACETYL-D-GLUCOSAMINE) |
NAG
|
| A |
SUGAR (ALPHA-D-MANNOSE) |
MAN
|
| A |
ZINC ION |
ZN
|
| A |
(4S)-2-METHYL-2,4-PENTANEDIOL |
MPD
|
|
|
