Crystal structure of anti-osteopontin antibody 23C3 in complex with its epitope peptide
The structure was published by Du, J., Hou, S., Zhong, C., et al., Wang, H., Guo, Y., and Ding, J., in 2008 in a paper entitled "Molecular basis of recognition of human osteopontin by 23C3, a potential therapeutic antibody for treatment of rheumatoid arthritis" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 3 biomacromolecules, namely Fab fragment of anti-osteopontin antibody 23C3, Light chain, Fab fragment of anti-osteopontin antibody 23C3, Heavy chain, and a peptide from osteopontin.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterotrimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: