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PDBe Entry: 3cwt view

Crystal Structure of an AlkA Host/Guest Complex 2'-fluoro-2'-deoxyinosine:Adenine Base Pair
Summary
Header hydrolase/DNAsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.3 Å, R-factor: 23.9%, Free R-factor: 28.0%, Spacegroup: P 1 21 1
Released 02/09/2008, deposition: 22/04/2008, last revision: 24/02/2009
Authors Bowman, B.R.search; Lee, S.search; Wang, S.search; Verdine, G.L.search
Primary citation Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
STRUCTUREsearch vol:16, pag:1166-1174 (2008) [PubMed ID 18682218 ]search
Keywords AlkAsearch, 2'-fluoro-2'-deoxyinosinesearch, DNA repairsearch, host/guest complexsearch, DNA structuresearch, DNA damagesearch, Hydrolasesearch, hydrolase/DNA COMPLEXsearch
EC 3.2.2.21 ExPASy BRENDA search (A B C D)
Organism Escherichia coli 562search(A B C D)
UniProt DNA-3-methyladenine glycosylase 2 (EC 3.2.2.21) (DNA-3-methyladenine glycosylase II) (3-methyladenine-DNA glycosylase II, inducible) (TAG II) (DNA-3-methyladenine glycosidase II) P04395search (A B C D)
Solvent A, B, C, D, E, H
Related entries 3cvs, 3cvt, 3cw7, 3cwa, 3cws, 3cwu
Polymers
Id Name Type UniProt Residues Observed
A, B, C, D DNA-3-methyladenine glycosylase 2 Protein P04395 (3MG2_ECOLI)search
282 100%
E, G DNA (5'-D(*DGP*DAP*DCP*DAP*DTP*DGP*DAP*(2FI)P*DTP*DGP*DCP*DC)-3') DNA
12 100%
F, H DNA (5'-D(*DGP*DGP*DCP*DAP*DAP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3') DNA
12 100%
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