3cmt Summary

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Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures

The structure was published by Chen, Z., Yang, H., and Pavletich, N.P., in 2008 in a paper entitled "Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.15 Å and deposited in 2008.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DCP*DCP*DCP*DAP*DCP*DCP*DTP*DTP*DTP*DT)-3'), DNA (5'-D(P*DGP*DGP*DTP*DGP*DGP*DG)-3'), and Protein recA.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Protein recA P0A7G6 (2-335) (RECA_ECOLI)search Escherichia coli K-12search 95% 1706 94%
D Protein recA P0A7G6 (2-335) (RECA_ECOLI)search Escherichia coli K-12search 95% 1706 94%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P0A7G6 (2 - 335) Protein recA Escherichia coli

Chain Sequence family (Pfam)
A, D (P0A7G6) PF00154: recA bacterial DNA recombination proteinsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, D (P0A7G6) single-stranded DNA bindingsearch nucleoside-triphosphatase activitysearch DNA bindingsearch ATP bindingsearch DNA-dependent ATPase activitysearch damaged DNA bindingsearch nucleotide bindingsearch protein bindingsearch DNA metabolic processsearch SOS responsesearch cell motilitysearch cellular response to DNA damage stimulussearch DNA recombinationsearch response to ionizing radiationsearch response to stresssearch DNA repairsearch ATP catabolic processsearch cytoplasmsearch

Chain InterPro annotation
A, D AAA+ ATPase domainsearch DNA recombination and repair protein RecAsearch DNA recombination/repair protein RecA, conserved sitesearch DNA recombination and repair protein RecA, monomer-monomer interfacesearch DNA recombination and repair protein RecA-like, ATP-binding domainsearch DNA recombination and repair protein RecA, C-terminalsearch P-loop containing nucleoside triphosphate hydrolasesearch