3cmt Summary

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Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures

The structure was published by Chen, Z., Yang, H., and Pavletich, N.P., in 2008 in a paper entitled "Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.15 Å and deposited in 2008.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DCP*DCP*DCP*DAP*DCP*DCP*DTP*DTP*DTP*DT)-3'), DNA (5'-D(P*DGP*DGP*DTP*DGP*DGP*DG)-3'), and Protein recA.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Protein recA P0A7G6 (2-335) (RECA_ECOLI)search Escherichia coli K-12search 95% 1706 94%
D Protein recA P0A7G6 (2-335) (RECA_ECOLI)search Escherichia coli K-12search 95% 1706 94%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P0A7G6 (2 - 335) Protein recA Escherichia coli

Chain Sequence family (Pfam)
A, D (P0A7G6) PF00154: recA bacterial DNA recombination proteinsearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A, D (P0A7G6) SOS responsesearch response to DNA damage stimulussearch DNA recombinationsearch DNA metabolic processsearch DNA repairsearch cell motilitysearch response to stresssearch DNA-dependent ATPase activitysearch DNA bindingsearch single-stranded DNA bindingsearch ATP bindingsearch nucleotide bindingsearch nucleoside-triphosphatase activitysearch protein bindingsearch damaged DNA bindingsearch cytoplasmsearch

Chain InterPro annotation
A, D AAA+ ATPase domainsearch DNA recombination and repair protein RecAsearch DNA recombination/repair protein RecA, conserved sitesearch DNA recombination/repair protein RecA, monomer-monomer interfacesearch DNA recombination/repair protein RecA/RadB, ATP-binding domainsearch DNA recombination and repair protein RecA, C-terminalsearch P-loop containing nucleoside triphosphate hydrolasesearch