3ckx Summary

pdbe.org/3ckx
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Crystal structure of sterile 20-like kinase 3 (MST3, STK24) in complex with staurosporine

A publication describing this structure is not available. The depositing authors are Antonysamy, S.S.search; Burley, S.K.search; Buchanan, S.search; Chau, F.search; Feil, I.search; Wu, L.search; Sauder, J.M.search; New York SGX Research Center for Structural Genomics (NYSGXRC)search

This crystal structure was determined using X-ray diffraction at a resolution of 2.7 Å and deposited in 2008.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Serine/threonine-protein kinase 24. This molecule has the UniProt identifier Q9Y6E0 (STK24_HUMAN)search. The sample contained 304 residues which is < 90% of the natural sequence. Out of 304 residues 267 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Serine/threonine-protein kinase 24 Q9Y6E0 (31-323) (STK24_HUMAN)search Homo sapienssearch < 90% 304 91%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9Y6E0 (31 - 323) Serine/threonine-protein kinase 24 Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A Phosphorylase Kinase; domain 1search, Transferase(Phosphotransferase) domain 1search Protein kinase domainsearch

Chain ID Biological process (GO) Molecular function (GO)
A (Q9Y6E0) protein phosphorylationsearch ATP bindingsearch protein kinase activitysearch transferase activity, transferring phosphorus-containing groupssearch

Chain InterPro annotation
A Protein kinase domainsearch Serine-threonine/tyrosine-protein kinase catalytic domainsearch Serine/threonine/dual specificity protein kinase, catalytic domainsearch Protein kinase-like domainsearch Protein kinase, ATP binding sitesearch