Human GRK2 in Complex with Gbetagamma subunits
The structure was published by Tesmer, J.J., Tesmer, V.M., Lodowski, D.T., Steinhagen, H., and Huber, J., in 2010 in a paper entitled "Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.75 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 3 biomacromolecules, namely Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, and Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterotrimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 3 unique UniProt proteins: