3ch2 Summary


Crystal Structure Analysis of SERA5E from plasmodium falciparum

The structure was published by Hodder, A.N., Malby, R.L., Clarke, O.B., et al., Colman, P.M., Crabb, B.S., and Smith, B.J., in 2009 in a paper entitled "Structural Insights into the Protease-like Antigen Plasmodium falciparum SERA5 and Its Noncanonical Active-Site Serine" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2008.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Serine-repeat antigen protein. This molecule has the UniProt identifier Q9TY95 (SERA_PLAF7)search. The sample contained 265 residues which is < 90% of the natural sequence. Out of 265 residues 249 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
X Serine-repeat antigen protein Q9TY95 (564-828) (SERA_PLAF7)search Plasmodium falciparum 3D7search < 90% 265 96%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9TY95 (564 - 828) Serine-repeat antigen protein Plasmodium falciparum 3D7

Chain Structural classification (CATH) Sequence family (Pfam)
X Cysteine proteinasessearch Papain family cysteine proteasesearch

Chain ID Molecular function (GO) Biological process (GO)
X (Q9TY95) cysteine-type peptidase activitysearch proteolysissearch

Chain InterPro annotation
X Peptidase C1A, papain C-terminalsearch Peptidase C1Asearch Cysteine peptidase, histidine active sitesearch Cysteine peptidase, asparagine active sitesearch