3cbs Summary

pdbe.org/3cbs
spacer

CELLULAR RETINOIC ACID BINDING PROTEIN II IN COMPLEX WITH A SYNTHETIC RETINOIC ACID (RO-12 7310)

The structure was published by Chaudhuri, B.N., Kleywegt, G.J., Broutin-L'Hermite, I., et al., Le Motte, P., Partouche, O., and Jones, T.A., in 1999 in a paper entitled "Structures of cellular retinoic acid binding proteins I and II in complex with synthetic retinoids." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 1999.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of PROTEIN (CRABP-II). This molecule has the UniProt identifier P29373 (RABP2_HUMAN)search. The sample contained 137 residues which is 99% of the natural sequence. Out of 137 residues 137 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROTEIN (CRABP-II) P29373 (2-138) (RABP2_HUMAN)search Homo sapienssearch 99% 137 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P29373 (2 - 138) PROTEIN (CRABP-II) Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P29373) Fatty acid binding protein-likesearch Lipocalinsearch PF00061: Lipocalin / cytosolic fatty-acid binding protein familysearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P29373) retinal bindingsearch transporter activitysearch lipid bindingsearch retinoid bindingsearch retinol bindingsearch extracellular vesicular exosomesearch endoplasmic reticulumsearch nucleussearch cytoplasmsearch nucleolussearch signal transductionsearch regulation of transcription, DNA-templatedsearch transportsearch epidermis developmentsearch

Chain InterPro annotation
A Cytosolic fatty-acid bindingsearch Lipocalin/cytosolic fatty-acid binding domainsearch Calycin-likesearch Calycinsearch