Crystal Structure of Hepatocyte Nuclear Factor 4alpha in complex with DNA: Diabetes Gene Product
The structure was published by Lu, P., Rha, G.B., Melikishvili, M., et al., Adkins, B.C., Fried, M.G., and Chi, Y.I., in 2008 in a paper entitled "Structural basis of natural promoter recognition by a unique nuclear receptor, HNF4alpha. Diabetes gene product." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 3 biomacromolecules, namely Hepatocyte Nuclear Factor 4-alpha promoter element DNA and Hepatocyte Nuclear Factor 4-alpha, DNA binding domain.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterotetramers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: