PDB entry 3c7i (supersedes 2huy)
X-RAY crystal structure of the complex between the grb2-sh2 domain and a flexible ligand, FPTVN.
The structure was published by Benfield, A.P., Teresk, M.G., Plake, H.R., Delorbe, J.E., Millspaugh, L.E., and Martin, S.F., in 2006 in a paper entitled "Ligand Preorganization May be Accompanied by Entropic Penalties in Protein-Ligand Interactions." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.7 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Growth factor receptor-bound protein 2. This molecule has the UniProt identifier P62993 (GRB2_HUMAN). The sample contained 116 residues which is < 90% of the natural sequence. Out of 116 residues 101 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: