3bhh Summary

pdbe.org/3bhh
spacer

Crystal structure of human calcium/calmodulin-dependent protein kinase IIB isoform 1 (CAMK2B)

A publication describing this structure is not available. The depositing authors are Filippakopoulos, P.search; Rellos, P.search; Niesen, F.search; Burgess, N.search; Bullock, A.search; Berridge, G.search; Pike, A.C.W.search; Ugochukwu, E.search; Pilka, E.S.search; von Delft, F.search; Arrowsmith, C.H.search; Edwards, A.M.search; Weigelt, J.search; Knapp, S.search; Structural Genomics Consortium (SGC)search

This crystal structure was determined using X-ray diffraction at a resolution of 2.4 Å and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Calcium/calmodulin-dependent protein kinase type II beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Calcium/calmodulin-dependent protein kinase type II beta chain Q13554 (11-303) (KCC2B_HUMAN)search Homo sapienssearch < 90% 295 97%
B Calcium/calmodulin-dependent protein kinase type II beta chain Q13554 (11-303) (KCC2B_HUMAN)search Homo sapienssearch < 90% 295 97%
C Calcium/calmodulin-dependent protein kinase type II beta chain Q13554 (11-303) (KCC2B_HUMAN)search Homo sapienssearch < 90% 295 97%
D Calcium/calmodulin-dependent protein kinase type II beta chain Q13554 (11-303) (KCC2B_HUMAN)search Homo sapienssearch < 90% 295 97%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q13554 (11 - 303) Calcium/calmodulin-dependent protein kinase type II beta chain Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A, B, C, D Transferase(Phosphotransferase) domain 1search Protein kinase domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A, B, C, D (Q13554) protein serine/threonine kinase activitysearch ATP bindingsearch protein kinase activitysearch transferase activity, transferring phosphorus-containing groupssearch protein phosphorylationsearch

Chain InterPro annotation
A, B, C, D Protein kinase domainsearch Serine/threonine/dual specificity protein kinase, catalytic domainsearch Serine/threonine-protein kinase, active sitesearch Protein kinase-like domainsearch Protein kinase, ATP binding sitesearch Calcium/calmodulin-dependent/calcium-dependent protein kinasesearch