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EBI PDBe PDBeView

PDBe Entry: 3bgv view

Crystal structure of mRNA cap guanine-N7 methyltransferase in complex with SAH
Summary
Header TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.3 Å, R-factor: 22.486%, Free R-factor: 29.448%, Spacegroup: P 21 21 21
Released 04/12/2007, deposition: 27/11/2007, last revision: 24/02/2009
Authors Lunin, V.V.search; Wu, H.search; Zeng, H.search; Antoshenko, T.search; MacKenzie, F.search; Weigelt, J.search; Arrowsmith, C.H.search; Edwards, A.M.search; Bochkarev, A.search; Min, J.search; Plotnikov, A.N.search; Structural Genomics Consortium (SGC)search
Primary citation The crystal structure of human RNA (guanine-7-) methyltransferase in complex with SAH.
To be Published
Keywords methyltransferasesearch, Alternative splicingsearch, mRNA cappingsearch, mRNA processingsearch, Nucleussearch, Phosphoproteinsearch, RNA-bindingsearch, S-adenosyl-L-methioninesearch, Structural Genomicssearch, Structural Genomics Consortiumsearch, SGCsearch
EC 2.1.1.56 ExPASy BRENDA search (A B C D)
Organism Homo sapiens(human) 9606search(A B C D)
UniProt mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine-N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase) (hcm1p) (hCMT1) (hMet) O43148search (A B C D)
Solvent A, B, C, D
Polymers
Id Name Type UniProt Residues Observed
A, B, C, D mRNA cap guanine-N7 methyltransferase Protein O43148 (MCES_HUMAN)search
 313 86%
Heterogens
Id Name Ligands
C S-ADENOSYL-L-HOMOCYSTEINE SAH search
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