› 3bfk

X-ray diffraction
1.8Å resolution

Crystal structure of Plasmodium falciparum Rab11a in complex with GDP

Released:
DOI: 10.2210/pdb3bfk/pdb
PDB entry 3bfk coloured by chain, front view.
PDB entry 3bfk coloured by chain, side view.
PDB entry 3bfk coloured by chain, top view.
Source organism: Plasmodium falciparum 3D7
Entry authors: Pizarro JC, Sukumar D, Hassanali A, Lin L, Wernimont AK, Lew J, Kozieradzki I, Edwards AM, Arrowsmith CH, Weigelt J, Sundstrom M, Bochkarev A, Hui R, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181189 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein Rab-11A Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 181 amino acids
Theoretical weight: 20.69 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli
UniProt:
  • Canonical: Q76NM4 (Residues: 6-185; Coverage: 83%)
Gene name: PF3D7_1320600
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand GDP 5 x GDP
Ligand GOL 3 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P21
Unit cell:
a: 83.49Å b: 48.371Å c: 119.236Å
α: 90° β: 92.36° γ: 90°
R-values:
R R work R free
0.22 0.218 0.259
Expression system: Escherichia coli

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