› 3b1f

X-ray diffraction
2.1Å resolution

Crystal structure of prephenate dehydrogenase from Streptococcus mutans

Released:
DOI: 10.2210/pdb3b1f/pdb
PDB entry 3b1f coloured by chain, front view.
PDB entry 3b1f coloured by chain, side view.
PDB entry 3b1f coloured by chain, top view.
Source organism: Streptococcus mutans
Primary publication:
Crystal structure of prephenate dehydrogenase from Streptococcus mutans.
Ku HK, Do NH, Song JS, Choi S, Yeon SH, Shin MH, Kim KJ, Park SR, Park IY, Kim SK, Lee SJ
Int. J. Biol. Macromol. 49 761-6 (2011)
PMID: 21798280

Function and Biology Details

Reaction catalysed: 
Prephenate + NAD(+) = 4-hydroxyphenylpyruvate + CO(2) + NADH
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184233 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Prephenate/arogenate dehydrogenase domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 290 amino acids
Theoretical weight: 32.6 KDa
Source organism: Streptococcus mutans
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8DUW0 (Residues: 1-287; Coverage: 78%)
Gene name: SMU_781
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand NAD 1 x NAD
No bound ligands
1 modified residue:
Ligand MSE 7 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 6C1
Spacegroup: C2221
Unit cell:
a: 79.34Å b: 145.624Å c: 77.552Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.193 0.234
Expression system: Escherichia coli

Quick links

Citations

6 citation in other articles

The usefulness of biotyping in the determination of selected pathogenicity determinants in Streptococcus mutans.
Krzyściak et al. (2014)
5 more