3ax2 Summary

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Crystal structure of rat TOM20-ALDH presequence complex: a disulfide-tethered complex with a non-optimized, long linker

The structure was published by Saitoh, T., Igura, M., Miyazaki, Y., Ose, T., Maita, N., and Kohda, D., in 2011 in a paper entitled "Crystallographic snapshots of tom20-mitochondrial presequence interactions with disulfide-stabilized peptides." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 2011.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Mitochondrial import receptor subunit TOM20 homolog and Aldehyde dehydrogenase, mitochondrial.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Mitochondrial import receptor subunit TOM20 homolog Q62760 (59-126) (TOM20_RAT)search Rattus norvegicussearch < 90% 73 95%
C Mitochondrial import receptor subunit TOM20 homolog Q62760 (59-126) (TOM20_RAT)search Rattus norvegicussearch < 90% 73 95%
E Mitochondrial import receptor subunit TOM20 homolog Q62760 (59-126) (TOM20_RAT)search Rattus norvegicussearch < 90% 73 95%
G Mitochondrial import receptor subunit TOM20 homolog Q62760 (59-126) (TOM20_RAT)search Rattus norvegicussearch < 90% 73 95%
B Aldehyde dehydrogenase, mitochondrial P11884 (12-20) (ALDH2_RAT)search Rattus norvegicussearch < 90% 16 100%
D Aldehyde dehydrogenase, mitochondrial P11884 (12-20) (ALDH2_RAT)search Rattus norvegicussearch < 90% 16 100%
F Aldehyde dehydrogenase, mitochondrial P11884 (12-20) (ALDH2_RAT)search Rattus norvegicussearch < 90% 16 100%
H Aldehyde dehydrogenase, mitochondrial P11884 (12-20) (ALDH2_RAT)search Rattus norvegicussearch < 90% 16 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
Q62760 (59 - 126) Mitochondrial import receptor subunit TOM20 homolog Rattus norvegicus
P11884 (12 - 20) Aldehyde dehydrogenase, mitochondrial Rattus norvegicus

Chain Sequence family (Pfam)
A, C, E, G MAS20 protein import receptorsearch
B, D, F, H

Chain ID Cellular component (GO) Biological process (GO)
A, C, E, G (Q62760) mitochondrial outer membrane translocase complexsearch protein targetingsearch intracellular protein transportsearch

Chain InterPro annotation
A, C, E, G Protein import receptor MAS20-relatedsearch Protein import receptor MAS20, metazoansearch Mitochondrial outer membrane translocase complex, subunit Tom20 domainsearch
B, D, F, H